Welcome to DeShPet
Our Service
The Design of Peptide libraries has never been easier. The DeShPet application utilizes NSGA-II genetic algorithm to search through the peptide chemical space and provide you with a plethora of solutions.
Our algorithm supports the design of Short peptides of lengths up to 15 that may consist of 20 natural amino acids. Using their single letter codes (R, H, K, D, E, S, T, N, Q, C, G, P, A, V, I, L, M, F, Y, W) and the colon symbol ':' to separate their positions within a sequence, you may customize your peptide library and optimize it to become focused and maximally diversified.
Peptide library optimization
Optimize your peptide library in terms of diversity by mass, hydrophobicity or charge.
Single or multiple library
Select a single or multiple library optimization approach.
Antimicrobial activity
Estimate the probability that a peptide exhibits antimicrobial activity using our sequential properties model (also available on Github).
Visualization
Visualize your solutions on Pareto front and sequence logo graphs.
Properties
Compute a number of physico-chemical properties for your library or arbitrary peptides.